Spotlight on Neurology

Credits: 0.25 CME
Gene Therapy for SMA: Data, Implications, and Global Perspectives — Importance of Early Diagnosis and Screening in SMA
Sharon Aharoni, MD
The France Foundation

Gene Therapy for SMA: Data, Implications, and Global Perspectives — Importance of Early Diagnosis and Screening in SMA

Start

Activity Details

Free CME
0.25 AMA PRA Category 1 Credit(s)
Released: October 1, 2020
Expires: September 30, 2021
15 minutes to complete

Accredited By

Target Audience

This activity will target neurologists, pediatricians, and geneticists, as well as other health care providers who may be involved in the management of patients with SMA.

Learning Objectives

  • Explore potential implications of gene therapy for SMA

Activity Description

This activity discusses new, emerging, and targeted treatments for SMA. The activity also explores the potential clinical challenges and how this affects phenotypes over time.

Statement of Educational Need

The rapid influx of information surrounding emerging treatments for SMA means that there are critical gaps in clinician knowledge and the ability to apply it in practice, creating a need for education to support clinicians who recognize, diagnose, and/or manage patients with SMA.

Faculty

Sharon Aharoni, MD
Director of SMA Therapies,
Schneider Institute of Child Neurology Children’s Medical Center
Petach Tikva, Israel

Sharon Aharoni, MD, has participated in contract research for AveXis.


Professor Enrico Bertini
Unit of Neuromuscular and Neurodegenerative Disorders
Laboratory of Molecular Medicine
Bambino Gesu' Children's Research Hospital
Rome, Italy

Professor Enrico Bertini has no financial relationships to disclose.


Professor Aviva Fattal-Valevski
Director, Pediatric Neurology Institute
Dana Children's Hospital, Tel Aviv Medical Center
Tel Aviv, Israel

Professor Aviva Fattal-Valevski has no financial relationships to disclose.


Professor Marcondes Cavalcante França Junior
Assistant Professor of Neurology
The University of Campinas
Sao Paulo, Brazil

Professor Marcondes Cavalcante França Junior has participated in advisory boards for AveXis, Biogen, and Roche.


Professor Wolfgang Mueller-Felber
Head of Center for Pediatric Neuromuscular Disorders
and Clinical Neurophysiology
Dr. von Hauner Children’s Hospital
Munich, Germany

Professor Wolfgang Mueller-Felber has participated in scientific advisory boards for Genzyme and has received research support from GlaxoSmithKline, Lilly, and Trophos.


J. Andoni Urtizberea, MD, MSc
Attending Physician
Institut de Myologie
Paris, France

J. Andoni Urtizberea, MD, MSc, has no financial relationships to disclose.


Conflict of Interest Policy/Disclosure Statement

In accordance with the ACCME Standards for Commercial Support, The France Foundation (TFF) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. TFF resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs. Furthermore, TFF seeks to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. TFF is committed to providing learners with high-quality CME/CE activities that promote improvements in health care and not those of a commercial interest.

Accreditation Statement

The France Foundation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation of Credit

Physicians
The France Foundation designates this enduring activity for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses
Nurses who are certified by the American Nurses Credentialing Center (ANCC) may utilize activities that are certified by ACCME-accredited providers toward their requirement for certification renewal by the ANCC. A certificate of attendance will be provided by The France Foundation, an ACCME accredited provider.

Method of Participation/How to Receive Credit

  • There are no fees for participating in and receiving credit for this activity.
  • Review the activity objectives and CME/CE information.
  • Complete the CME/CE activity.
  • Complete the online posttest. A score of at least 66% is required to complete this activity. The participant may take the test until successfully passed.
  • Complete the CME/CE evaluation/attestation form. The form provides each participant the opportunity to comment on how the activity will affect their professional practice; the quality of the instructional process; the perception of enhanced professional effectiveness; the perception of commercial bias; and his/her views on future educational needs.
  • Credit documentation/reporting:
    • If you are requesting AMA PRA Category 1 Credits™ or a certificate of participation—your CME/CE certificate will be available for download.

Statement of Commercial Support

This activity is supported by an educational grant from AveXis.

Disclaimer Statement/Disclosure of Unlabeled Use

The France Foundation presents this information for educational purposes only. The content is provided solely by faculty who have been selected because of their recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The France Foundation and the commercial supporter(s) assume no liability for the information herein.

Contact Information for Questions About the Activity

If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or info@francefoundation.com.

Activity Details

Free CME
0.25 AMA PRA Category 1 Credit(s)
Released: October 1, 2020
Expires: September 30, 2021
15 minutes to complete

Accredited By

Target Audience

This activity will target neurologists, pediatricians, and geneticists, as well as other health care providers who may be involved in the management of patients with SMA.

Learning Objectives

  • Explore potential implications of gene therapy for SMA

Activity Description

This activity discusses new, emerging, and targeted treatments for SMA. The activity also explores the potential clinical challenges and how this affects phenotypes over time.

Statement of Educational Need

The rapid influx of information surrounding emerging treatments for SMA means that there are critical gaps in clinician knowledge and the ability to apply it in practice, creating a need for education to support clinicians who recognize, diagnose, and/or manage patients with SMA.

Faculty

Sharon Aharoni, MD
Director of SMA Therapies,
Schneider Institute of Child Neurology Children’s Medical Center
Petach Tikva, Israel

Sharon Aharoni, MD, has participated in contract research for AveXis.


Professor Enrico Bertini
Unit of Neuromuscular and Neurodegenerative Disorders
Laboratory of Molecular Medicine
Bambino Gesu' Children's Research Hospital
Rome, Italy

Professor Enrico Bertini has no financial relationships to disclose.


Professor Aviva Fattal-Valevski
Director, Pediatric Neurology Institute
Dana Children's Hospital, Tel Aviv Medical Center
Tel Aviv, Israel

Professor Aviva Fattal-Valevski has no financial relationships to disclose.


Professor Marcondes Cavalcante França Junior
Assistant Professor of Neurology
The University of Campinas
Sao Paulo, Brazil

Professor Marcondes Cavalcante França Junior has participated in advisory boards for AveXis, Biogen, and Roche.


Professor Wolfgang Mueller-Felber
Head of Center for Pediatric Neuromuscular Disorders
and Clinical Neurophysiology
Dr. von Hauner Children’s Hospital
Munich, Germany

Professor Wolfgang Mueller-Felber has participated in scientific advisory boards for Genzyme and has received research support from GlaxoSmithKline, Lilly, and Trophos.


J. Andoni Urtizberea, MD, MSc
Attending Physician
Institut de Myologie
Paris, France

J. Andoni Urtizberea, MD, MSc, has no financial relationships to disclose.


Conflict of Interest Policy/Disclosure Statement

In accordance with the ACCME Standards for Commercial Support, The France Foundation (TFF) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. TFF resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs. Furthermore, TFF seeks to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. TFF is committed to providing learners with high-quality CME/CE activities that promote improvements in health care and not those of a commercial interest.

Accreditation Statement

The France Foundation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation of Credit

Physicians
The France Foundation designates this enduring activity for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses
Nurses who are certified by the American Nurses Credentialing Center (ANCC) may utilize activities that are certified by ACCME-accredited providers toward their requirement for certification renewal by the ANCC. A certificate of attendance will be provided by The France Foundation, an ACCME accredited provider.

Method of Participation/How to Receive Credit

  • There are no fees for participating in and receiving credit for this activity.
  • Review the activity objectives and CME/CE information.
  • Complete the CME/CE activity.
  • Complete the online posttest. A score of at least 66% is required to complete this activity. The participant may take the test until successfully passed.
  • Complete the CME/CE evaluation/attestation form. The form provides each participant the opportunity to comment on how the activity will affect their professional practice; the quality of the instructional process; the perception of enhanced professional effectiveness; the perception of commercial bias; and his/her views on future educational needs.
  • Credit documentation/reporting:
    • If you are requesting AMA PRA Category 1 Credits™ or a certificate of participation—your CME/CE certificate will be available for download.

Statement of Commercial Support

This activity is supported by an educational grant from AveXis.

Disclaimer Statement/Disclosure of Unlabeled Use

The France Foundation presents this information for educational purposes only. The content is provided solely by faculty who have been selected because of their recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The France Foundation and the commercial supporter(s) assume no liability for the information herein.

Contact Information for Questions About the Activity

If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or info@francefoundation.com.

Neurology Presentations

0.25 CME
Vindico
Sarcoidosis: Considerations in the Management of Refractory Disease - Pulmonary Sarcoidosis

Sarcoidosis: Considerations in the Management of Refractory Disease - Pulmonary Sarcoidosis

Start

Activity Details

Free CME
0.25 AMA PRA Category 1 Credit(s)
Released: February 11, 2020
Expires: February 10, 2021
15 minutes to complete

Accredited By

This continuing medical education activity is provided by

Target Audience

The intended audience for the activity is pulmonologists, neurologists, cardiologists, and other health care professionals involved in the management of patients with sarcoidosis.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:
  • Incorporate knowledge of available clinical evidence to select among treatment options for refractory sarcoidosis.
  • Implement strategies to optimize patient-centered care and coordination within a multidisciplinary care team.

Activity Description

Sarcoidosis is a multisystem inflammatory disease that can affect 1 or more organs. It is newly diagnosed in an estimated 25,000 persons each year, with approximately 185,000 patients seeking medical care per year. Sarcoidosis most often affects the lung, but it is highly variable and almost any organ can be affected. Cutaneous, ocular, renal, cardiac, neurologic, gastrointestinal, and musculoskeletal manifestations are possible. Although many patients respond to first-line therapy or experience spontaneous resolution of the condition, a subset of patients are refractory to initial therapy, experiencing significant morbidity and mortality associated with disease progression as well as sarcoidosis-associated complications. In this educational activity, expert clinicians will discuss optimal ways to diagnose and manage patients with sarcoidosis.

Agenda

  • Pulmonary Sarcoidosis
    • Faculty: Dr. Culver and Dr. Marts

Faculty

Activity Chair

Daniel Culver, DO
Director, Interstitial Lung Disease Program
Cleveland Clinic
Cleveland, OH

Disclosure:
Consulting Fee: aTyr Pharma
Contracted Research: aTyr Pharma, Foundation for Sarcoidosis Research, Mallinkrodt



Faculty

Lucian T. Marts, MD
Assistant Professor
Emory University School of Medicine
Atlanta, Georgia

Disclosure:
Contracted Research: aTyr Pharma


Divya Patel, DO
Clinical Assistant Professor
Division of Pulmonary, Critical Care & Sleep Medicine
University of Florida Health
Gainesville, Florida

Disclosure: No relevant financial relationships to disclose.


Reviewer:
Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Disclosure: No relevant financial relationships to disclose.


Vindico Medical Education Staff:
Disclosure: No relevant financial relationships to disclose.


Signed Disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Conflict of Interest Policy/Disclosure Statement

In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears above.

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation of Credit

Vindico Medical Education designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, February 11, 2020 to February 10, 2021.

How to Participate in this Activity and Obtain CME Credit

To participate in this activity, you must read the objectives, answer the pretest question, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering the posttest question correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.

CME for MIPS Improvement Activity

MIPS Qualifying Activity:
Vindico has identified this CME activity as an improvement activity in the Merit-Based Incentive Payment System (MIPS) of the Quality Payment Program (QPP). Participants who successfully complete the activity and its performance assessment will receive printable documentation of successful completion for MIPS self-reporting.

To meet the criteria for improvement activities in the MIPS of QPP, accredited CME providers need to implement activities that:

  • address a quality or safety gap that is supported by a needs assessment or problem analysis, or support the completion of such a needs assessment as part of the activity;
  • have specific, measurable aim(s) for improvement;
  • include interventions intended to result in improvement;
  • include data collection and analysis of performance data to assess the impact of the interventions; and
  • define meaningful clinician participation in their activity, describe the mechanism for identifying clinicians who meet the requirements, and provide participant completion information.

Statement of Commercial Support

This activity is supported by an educational grant from Mallinckrodt Pharmaceuticals.

Disclaimer Statement/Disclosure of Unlabeled Use

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2020 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME Questions?

Contact us at CME@VindicoCME.com

Activity Details

Free CME
0.25 AMA PRA Category 1 Credit(s)
Released: February 11, 2020
Expires: February 10, 2021
15 minutes to complete

Accredited By

This continuing medical education activity is provided by

Target Audience

The intended audience for the activity is pulmonologists, neurologists, cardiologists, and other health care professionals involved in the management of patients with sarcoidosis.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:
  • Incorporate knowledge of available clinical evidence to select among treatment options for refractory sarcoidosis.
  • Implement strategies to optimize patient-centered care and coordination within a multidisciplinary care team.

Activity Description

Sarcoidosis is a multisystem inflammatory disease that can affect 1 or more organs. It is newly diagnosed in an estimated 25,000 persons each year, with approximately 185,000 patients seeking medical care per year. Sarcoidosis most often affects the lung, but it is highly variable and almost any organ can be affected. Cutaneous, ocular, renal, cardiac, neurologic, gastrointestinal, and musculoskeletal manifestations are possible. Although many patients respond to first-line therapy or experience spontaneous resolution of the condition, a subset of patients are refractory to initial therapy, experiencing significant morbidity and mortality associated with disease progression as well as sarcoidosis-associated complications. In this educational activity, expert clinicians will discuss optimal ways to diagnose and manage patients with sarcoidosis.

Agenda

  • Pulmonary Sarcoidosis
    • Faculty: Dr. Culver and Dr. Marts

Faculty

Activity Chair

Daniel Culver, DO
Director, Interstitial Lung Disease Program
Cleveland Clinic
Cleveland, OH

Disclosure:
Consulting Fee: aTyr Pharma
Contracted Research: aTyr Pharma, Foundation for Sarcoidosis Research, Mallinkrodt



Faculty

Lucian T. Marts, MD
Assistant Professor
Emory University School of Medicine
Atlanta, Georgia

Disclosure:
Contracted Research: aTyr Pharma


Divya Patel, DO
Clinical Assistant Professor
Division of Pulmonary, Critical Care & Sleep Medicine
University of Florida Health
Gainesville, Florida

Disclosure: No relevant financial relationships to disclose.


Reviewer:
Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Disclosure: No relevant financial relationships to disclose.


Vindico Medical Education Staff:
Disclosure: No relevant financial relationships to disclose.


Signed Disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Conflict of Interest Policy/Disclosure Statement

In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears above.

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation of Credit

Vindico Medical Education designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, February 11, 2020 to February 10, 2021.

How to Participate in this Activity and Obtain CME Credit

To participate in this activity, you must read the objectives, answer the pretest question, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering the posttest question correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.

CME for MIPS Improvement Activity

MIPS Qualifying Activity:
Vindico has identified this CME activity as an improvement activity in the Merit-Based Incentive Payment System (MIPS) of the Quality Payment Program (QPP). Participants who successfully complete the activity and its performance assessment will receive printable documentation of successful completion for MIPS self-reporting.

To meet the criteria for improvement activities in the MIPS of QPP, accredited CME providers need to implement activities that:

  • address a quality or safety gap that is supported by a needs assessment or problem analysis, or support the completion of such a needs assessment as part of the activity;
  • have specific, measurable aim(s) for improvement;
  • include interventions intended to result in improvement;
  • include data collection and analysis of performance data to assess the impact of the interventions; and
  • define meaningful clinician participation in their activity, describe the mechanism for identifying clinicians who meet the requirements, and provide participant completion information.

Statement of Commercial Support

This activity is supported by an educational grant from Mallinckrodt Pharmaceuticals.

Disclaimer Statement/Disclosure of Unlabeled Use

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2020 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME Questions?

Contact us at CME@VindicoCME.com

0.25 CME
Vindico
Sarcoidosis: Considerations in the Management of Refractory Disease - Cardiac Sarcoidosis

Sarcoidosis: Considerations in the Management of Refractory Disease - Cardiac Sarcoidosis

Start

Activity Details

Free CME
0.25 AMA PRA Category 1 Credit(s)
Released: February 11, 2020
Expires: February 10, 2021
15 minutes to complete

Accredited By

This continuing medical education activity is provided by

Target Audience

The intended audience for the activity is pulmonologists, neurologists, cardiologists, and other health care professionals involved in the management of patients with sarcoidosis.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:
  • Identify the clinical signs and symptoms of pulmonary and extrapulmonary manifestations of sarcoidosis.
  • Utilize available assessments to appropriately identify refractory or progressive disease.
  • Incorporate knowledge of available clinical evidence to select among treatment options for refractory sarcoidosis.
  • Implement strategies to optimize patient-centered care and coordination within a multidisciplinary care team.

Activity Description

Sarcoidosis is a multisystem inflammatory disease that can affect 1 or more organs. It is newly diagnosed in an estimated 25,000 persons each year, with approximately 185,000 patients seeking medical care per year. Sarcoidosis most often affects the lung, but it is highly variable and almost any organ can be affected. Cutaneous, ocular, renal, cardiac, neurologic, gastrointestinal, and musculoskeletal manifestations are possible. Although many patients respond to first-line therapy or experience spontaneous resolution of the condition, a subset of patients are refractory to initial therapy, experiencing significant morbidity and mortality associated with disease progression as well as sarcoidosis-associated complications. In this educational activity, expert clinicians will discuss optimal ways to diagnose and manage patients with sarcoidosis.

Agenda

  • Cardiac Sarcoidosis
    • Faculty: Dr. Culver and Dr. Patel

Faculty

Activity Chair

Daniel Culver, DO
Director, Interstitial Lung Disease Program
Cleveland Clinic
Cleveland, OH

Disclosure:
Consulting Fee: aTyr Pharma
Contracted Research: aTyr Pharma, Foundation for Sarcoidosis Research, Mallinkrodt



Faculty

Lucian T. Marts, MD
Assistant Professor
Emory University School of Medicine
Atlanta, Georgia

Disclosure:
Contracted Research: aTyr Pharma


Divya Patel, DO
Clinical Assistant Professor
Division of Pulmonary, Critical Care & Sleep Medicine
University of Florida Health
Gainesville, Florida

Disclosure: No relevant financial relationships to disclose.


Reviewer:
Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Disclosure: No relevant financial relationships to disclose.


Vindico Medical Education Staff:
Disclosure: No relevant financial relationships to disclose.


Signed Disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Conflict of Interest Policy/Disclosure Statement

In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears above.

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation of Credit

Vindico Medical Education designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, February 11, 2020 to February 10, 2021.

How to Participate in this Activity and Obtain CME Credit

To participate in this activity, you must read the objectives, answer the pretest question, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering the posttest question correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.

CME for MIPS Improvement Activity

MIPS Qualifying Activity:
Vindico has identified this CME activity as an improvement activity in the Merit-Based Incentive Payment System (MIPS) of the Quality Payment Program (QPP). Participants who successfully complete the activity and its performance assessment will receive printable documentation of successful completion for MIPS self-reporting.

To meet the criteria for improvement activities in the MIPS of QPP, accredited CME providers need to implement activities that:

  • address a quality or safety gap that is supported by a needs assessment or problem analysis, or support the completion of such a needs assessment as part of the activity;
  • have specific, measurable aim(s) for improvement;
  • include interventions intended to result in improvement;
  • include data collection and analysis of performance data to assess the impact of the interventions; and
  • define meaningful clinician participation in their activity, describe the mechanism for identifying clinicians who meet the requirements, and provide participant completion information.

Statement of Commercial Support

This activity is supported by an educational grant from Mallinckrodt Pharmaceuticals.

Disclaimer Statement/Disclosure of Unlabeled Use

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2020 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME Questions?

Contact us at CME@VindicoCME.com

Activity Details

Free CME
0.25 AMA PRA Category 1 Credit(s)
Released: February 11, 2020
Expires: February 10, 2021
15 minutes to complete

Accredited By

This continuing medical education activity is provided by

Target Audience

The intended audience for the activity is pulmonologists, neurologists, cardiologists, and other health care professionals involved in the management of patients with sarcoidosis.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:
  • Identify the clinical signs and symptoms of pulmonary and extrapulmonary manifestations of sarcoidosis.
  • Utilize available assessments to appropriately identify refractory or progressive disease.
  • Incorporate knowledge of available clinical evidence to select among treatment options for refractory sarcoidosis.
  • Implement strategies to optimize patient-centered care and coordination within a multidisciplinary care team.

Activity Description

Sarcoidosis is a multisystem inflammatory disease that can affect 1 or more organs. It is newly diagnosed in an estimated 25,000 persons each year, with approximately 185,000 patients seeking medical care per year. Sarcoidosis most often affects the lung, but it is highly variable and almost any organ can be affected. Cutaneous, ocular, renal, cardiac, neurologic, gastrointestinal, and musculoskeletal manifestations are possible. Although many patients respond to first-line therapy or experience spontaneous resolution of the condition, a subset of patients are refractory to initial therapy, experiencing significant morbidity and mortality associated with disease progression as well as sarcoidosis-associated complications. In this educational activity, expert clinicians will discuss optimal ways to diagnose and manage patients with sarcoidosis.

Agenda

  • Cardiac Sarcoidosis
    • Faculty: Dr. Culver and Dr. Patel

Faculty

Activity Chair

Daniel Culver, DO
Director, Interstitial Lung Disease Program
Cleveland Clinic
Cleveland, OH

Disclosure:
Consulting Fee: aTyr Pharma
Contracted Research: aTyr Pharma, Foundation for Sarcoidosis Research, Mallinkrodt



Faculty

Lucian T. Marts, MD
Assistant Professor
Emory University School of Medicine
Atlanta, Georgia

Disclosure:
Contracted Research: aTyr Pharma


Divya Patel, DO
Clinical Assistant Professor
Division of Pulmonary, Critical Care & Sleep Medicine
University of Florida Health
Gainesville, Florida

Disclosure: No relevant financial relationships to disclose.


Reviewer:
Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Disclosure: No relevant financial relationships to disclose.


Vindico Medical Education Staff:
Disclosure: No relevant financial relationships to disclose.


Signed Disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Conflict of Interest Policy/Disclosure Statement

In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears above.

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation of Credit

Vindico Medical Education designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, February 11, 2020 to February 10, 2021.

How to Participate in this Activity and Obtain CME Credit

To participate in this activity, you must read the objectives, answer the pretest question, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering the posttest question correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.

CME for MIPS Improvement Activity

MIPS Qualifying Activity:
Vindico has identified this CME activity as an improvement activity in the Merit-Based Incentive Payment System (MIPS) of the Quality Payment Program (QPP). Participants who successfully complete the activity and its performance assessment will receive printable documentation of successful completion for MIPS self-reporting.

To meet the criteria for improvement activities in the MIPS of QPP, accredited CME providers need to implement activities that:

  • address a quality or safety gap that is supported by a needs assessment or problem analysis, or support the completion of such a needs assessment as part of the activity;
  • have specific, measurable aim(s) for improvement;
  • include interventions intended to result in improvement;
  • include data collection and analysis of performance data to assess the impact of the interventions; and
  • define meaningful clinician participation in their activity, describe the mechanism for identifying clinicians who meet the requirements, and provide participant completion information.

Statement of Commercial Support

This activity is supported by an educational grant from Mallinckrodt Pharmaceuticals.

Disclaimer Statement/Disclosure of Unlabeled Use

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2020 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME Questions?

Contact us at CME@VindicoCME.com

0.25 CME
Vindico
Sarcoidosis: Considerations in the Management of Refractory Disease - Comprehensive Management of Sarcoidosis

Sarcoidosis: Considerations in the Management of Refractory Disease - Comprehensive Management of Sarcoidosis

Start

Activity Details

Free CME
0.25 AMA PRA Category 1 Credit(s)
Released: February 11, 2020
Expires: February 10, 2021
15 minutes to complete

Accredited By

This continuing medical education activity is provided by

Target Audience

The intended audience for the activity is pulmonologists, neurologists, cardiologists, and other health care professionals involved in the management of patients with sarcoidosis.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:
  • Identify the clinical signs and symptoms of pulmonary and extrapulmonary manifestations of sarcoidosis.
  • Utilize available assessments to appropriately identify refractory or progressive disease.
  • Implement strategies to optimize patient-centered care and coordination within a multidisciplinary care team.

Activity Description

Sarcoidosis is a multisystem inflammatory disease that can affect 1 or more organs. It is newly diagnosed in an estimated 25,000 persons each year, with approximately 185,000 patients seeking medical care per year. Sarcoidosis most often affects the lung, but it is highly variable and almost any organ can be affected. Cutaneous, ocular, renal, cardiac, neurologic, gastrointestinal, and musculoskeletal manifestations are possible. Although many patients respond to first-line therapy or experience spontaneous resolution of the condition, a subset of patients are refractory to initial therapy, experiencing significant morbidity and mortality associated with disease progression as well as sarcoidosis-associated complications. In this educational activity, expert clinicians will discuss optimal ways to diagnose and manage patients with sarcoidosis.

Agenda

  • Intro video
  • Comprehensive Management of Sarcoidosis
    • Faculty: Dr. Patel and Dr. Marts

Faculty

Activity Chair

Daniel Culver, DO
Director, Interstitial Lung Disease Program
Cleveland Clinic
Cleveland, OH

Disclosure:
Consulting Fee: aTyr Pharma
Contracted Research: aTyr Pharma, Foundation for Sarcoidosis Research, Mallinkrodt



Faculty

Lucian T. Marts, MD
Assistant Professor
Emory University School of Medicine
Atlanta, Georgia

Disclosure:
Contracted Research: aTyr Pharma


Divya Patel, DO
Clinical Assistant Professor
Division of Pulmonary, Critical Care & Sleep Medicine
University of Florida Health
Gainesville, Florida

Disclosure: No relevant financial relationships to disclose.


Reviewer:
Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Disclosure: No relevant financial relationships to disclose.


Vindico Medical Education Staff:
Disclosure: No relevant financial relationships to disclose.


Signed Disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Conflict of Interest Policy/Disclosure Statement

In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears above.

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation of Credit

Vindico Medical Education designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, February 11, 2020 to February 10, 2021.

How to Participate in this Activity and Obtain CME Credit

To participate in this activity, you must read the objectives, answer the pretest question, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering the posttest question correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.

CME for MIPS Improvement Activity

MIPS Qualifying Activity:
Vindico has identified this CME activity as an improvement activity in the Merit-Based Incentive Payment System (MIPS) of the Quality Payment Program (QPP). Participants who successfully complete the activity and its performance assessment will receive printable documentation of successful completion for MIPS self-reporting.

To meet the criteria for improvement activities in the MIPS of QPP, accredited CME providers need to implement activities that:

  • address a quality or safety gap that is supported by a needs assessment or problem analysis, or support the completion of such a needs assessment as part of the activity;
  • have specific, measurable aim(s) for improvement;
  • include interventions intended to result in improvement;
  • include data collection and analysis of performance data to assess the impact of the interventions; and
  • define meaningful clinician participation in their activity, describe the mechanism for identifying clinicians who meet the requirements, and provide participant completion information.

Statement of Commercial Support

This activity is supported by an educational grant from Mallinckrodt Pharmaceuticals.

Disclaimer Statement/Disclosure of Unlabeled Use

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2020 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME Questions?

Contact us at CME@VindicoCME.com

Activity Details

Free CME
0.25 AMA PRA Category 1 Credit(s)
Released: February 11, 2020
Expires: February 10, 2021
15 minutes to complete

Accredited By

This continuing medical education activity is provided by

Target Audience

The intended audience for the activity is pulmonologists, neurologists, cardiologists, and other health care professionals involved in the management of patients with sarcoidosis.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:
  • Identify the clinical signs and symptoms of pulmonary and extrapulmonary manifestations of sarcoidosis.
  • Utilize available assessments to appropriately identify refractory or progressive disease.
  • Implement strategies to optimize patient-centered care and coordination within a multidisciplinary care team.

Activity Description

Sarcoidosis is a multisystem inflammatory disease that can affect 1 or more organs. It is newly diagnosed in an estimated 25,000 persons each year, with approximately 185,000 patients seeking medical care per year. Sarcoidosis most often affects the lung, but it is highly variable and almost any organ can be affected. Cutaneous, ocular, renal, cardiac, neurologic, gastrointestinal, and musculoskeletal manifestations are possible. Although many patients respond to first-line therapy or experience spontaneous resolution of the condition, a subset of patients are refractory to initial therapy, experiencing significant morbidity and mortality associated with disease progression as well as sarcoidosis-associated complications. In this educational activity, expert clinicians will discuss optimal ways to diagnose and manage patients with sarcoidosis.

Agenda

  • Intro video
  • Comprehensive Management of Sarcoidosis
    • Faculty: Dr. Patel and Dr. Marts

Faculty

Activity Chair

Daniel Culver, DO
Director, Interstitial Lung Disease Program
Cleveland Clinic
Cleveland, OH

Disclosure:
Consulting Fee: aTyr Pharma
Contracted Research: aTyr Pharma, Foundation for Sarcoidosis Research, Mallinkrodt



Faculty

Lucian T. Marts, MD
Assistant Professor
Emory University School of Medicine
Atlanta, Georgia

Disclosure:
Contracted Research: aTyr Pharma


Divya Patel, DO
Clinical Assistant Professor
Division of Pulmonary, Critical Care & Sleep Medicine
University of Florida Health
Gainesville, Florida

Disclosure: No relevant financial relationships to disclose.


Reviewer:
Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Disclosure: No relevant financial relationships to disclose.


Vindico Medical Education Staff:
Disclosure: No relevant financial relationships to disclose.


Signed Disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Conflict of Interest Policy/Disclosure Statement

In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears above.

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation of Credit

Vindico Medical Education designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, February 11, 2020 to February 10, 2021.

How to Participate in this Activity and Obtain CME Credit

To participate in this activity, you must read the objectives, answer the pretest question, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering the posttest question correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.

CME for MIPS Improvement Activity

MIPS Qualifying Activity:
Vindico has identified this CME activity as an improvement activity in the Merit-Based Incentive Payment System (MIPS) of the Quality Payment Program (QPP). Participants who successfully complete the activity and its performance assessment will receive printable documentation of successful completion for MIPS self-reporting.

To meet the criteria for improvement activities in the MIPS of QPP, accredited CME providers need to implement activities that:

  • address a quality or safety gap that is supported by a needs assessment or problem analysis, or support the completion of such a needs assessment as part of the activity;
  • have specific, measurable aim(s) for improvement;
  • include interventions intended to result in improvement;
  • include data collection and analysis of performance data to assess the impact of the interventions; and
  • define meaningful clinician participation in their activity, describe the mechanism for identifying clinicians who meet the requirements, and provide participant completion information.

Statement of Commercial Support

This activity is supported by an educational grant from Mallinckrodt Pharmaceuticals.

Disclaimer Statement/Disclosure of Unlabeled Use

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2020 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME Questions?

Contact us at CME@VindicoCME.com

1.75 CME / CNE
Vindico
Best of MS Forum® VI: Applying the Latest Data and Advanced Communication to Individualize Treatment and Improve Quality Care

Best of MS Forum® VI: Applying the Latest Data and Advanced Communication to Individualize Treatment and Improve Quality Care

Start

Activity Details

Free CME/CNE
1.75 AMA PRA Category 1 Credit(s)
1.75 Contact Hour(s)
Released: January 24, 2020
Expires: January 23, 2021
1.75 hours to complete

Accredited By

This continuing education activity is provided by

Endorsed by:

Target Audience

The intended audience for this activity is neurologists, neurology nurses, and other health care professionals involved in the management of patients with multiple sclerosis (MS).

Learning Objectives

Upon successful completion of this activity, participants should be better able to:
Physicians and Nurses:

  • Evaluate the latest clinical and/or real-world evidence regarding available and emerging disease-modifying therapies (DMTs) for MS management.
  • Assess the burden of comorbidities for patients with MS and implications for treatment, medication management, and quality of life.
  • Examine emerging clinical trends and controversies in MS that may impact future clinical decision making.
  • Incorporate appropriate shared decision-making strategies to engage patients with MS in their own care.

Physicians Only:

  • Identify patients with relapsing-remitting MS (RRMS) or progressive MS in a timely manner to ensure appropriate intervention.
  • Select treatment for patients with RRMS or progressive MS based on the latest clinical advances, patient risk, and evidence-based recommendations.

Activity Description

Multiple sclerosis (MS) is a chronic, often disabling disease that attacks the central nervous system. The management of patients with MS is highly complex, and the development of disease-modifying therapies (DMTs) has dramatically altered the treatment paradigm. Clinicians need to be updated on new evidence-based recommendations on the use of DMTs from the American Academy of Neurology Guidelines released in 2018. Another important aspect of caring for patients with MS is communication. Patients must be not only educated about their disease and treatment options, but also engaged in conversations about their risk tolerance, quality of life—including symptoms that they are experiencing—and any concerns they may have regarding their care. Shared decision-making is a model of 2-way communication between a patient and a provider with established ability to improve a patient’s satisfaction of care. In this CME/CNE activity, MS Forum® VI, current treatment guidelines, gender-based issues, environmental factors, and comorbidities in MS are discussed alongside the safety, efficacy, and use of current DMTs.

Faculty

Activity Chair

Patricia K. Coyle, MD, FAAN, FANA
Professor and Vice Chair (Clinical Affairs)
Department of Neurology
Director
Multiple Sclerosis Comprehensive Care Center
Stony Brook University Medical Center
Stony Brook, NY
Disclosures
Consulting Fee: Accordant, Actelion, Alexion, Bayer, Biogen, Celgene, EMD Serono, Genentech/Roche, Novartis, Sanofi Genzyme, TG Therapeutics
Contracted Research:
Actelion, Alkermes, Genentech/Roche, MedDay, NINDS, Novartis



Faculty

Bruce A. Cohen, MD, FAAN, FANA, FACP
Professor of Neurology
Northwestern University
Feinberg School of Medicine
Director
Northwestern Comprehensive Multiple Sclerosis Program
Chicago, IL
Disclosures
Consulting Fee:
Biogen, EMD Serono, Genentech, Mylan
Contracted Research: MedDay, Roche/Genentech



Clyde E. Markowitz, MD
Associate Professor of Neurology
Director, Multiple Sclerosis Center
Hospital of the University of Pennsylvania
Perelman School of Medicine
Philadelphia, PA
Disclosures
Consulting Fee: Actelion, Alexion, Bayer, Biogen Idec, Celgene, Genentech/Roche, Genzyme/Sanofi, Merck/EMD Serono, Novartis, Teva
Contracted Research: Actelion, Genentech/Roche, Novartis



Claire S. Riley, MD
Assistant Professor of Neurology
Medical Director, Columbia Multiple Sclerosis Center
Department of Neurology, Columbia University
New York, NY
Disclosures
Consulting Fee: Biogen Idec, EMD Serono, Genentech, Genzyme, TG Therapeutics
Contracted Research: Biogen Idec


Reviewer

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.


Nurse Planners

Barbara A. Niedz, PhD, RN, CPHQ
No relevant financial relationships to disclose.


Amy Perrin-Ross, APN, MSN, CNRN, MSCN
Consulting Fee: Celgene, Genentech, Genzyme, Mallinckrodt, Novartis, Roche
Speakers Bureau: Biogen, EMD Serono, Genentech, Genzyme, Mallinckrodt, Novartis, Teva


Staff

Vindico Medical Education
No relevant financial relationships to disclose.


Conflict of Interest Policy/Disclosure Statement

In accordance with the Accreditation Council for Continuing Medical Education and the American Nurses Credentialing Center’s (ANCC’s) Commission on Accreditation’s Standards for Commercial Support, all CME/CNE providers are required to disclose to the activity audience the relevant financial relationships of the planners, faculty, reviewers and staff involved in the development of CME/CNE content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the CME/CNE activity content over which the individual has control.

Signed Disclosure(s) are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Vindico Medical Education, LLC, is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

Designation of Credit

Vindico Medical Education designates this enduring material for a maximum of 1.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Vindico Medical Education will provide 1.75 contact hours for nurses.

This enduring material is approved for 1 year from the date of original release, January 24, 2020 to January 23, 2021.

Instructions for Receiving Credit

To participate in this CME/CNE activity, you must read the objectives, answer the pretest questions, watch the presentations, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 4 out of 6 of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate or Learner-Paced Continuing Nursing Education Contact Hour Certificate.



MIPS Qualifying Activity
Vindico has identified this CME activity as an improvement activity in the Merit-Based Incentive Payment System (MIPS) of the Quality Payment Program (QPP). Participants who successfully complete the activity and its performance assessment will receive printable documentation of successful completion for MIPS self-reporting.

To meet the criteria for improvement activities in the MIPS of QPP, accredited CME providers need to implement activities that:

  • address a quality or safety gap that is supported by a needs assessment or problem analysis, or support the completion of such a needs assessment as part of the activity;
  • have specific, measurable aim(s) for improvement;
  • include interventions intended to result in improvement;
  • include data collection and analysis of performance data to assess the impact of the interventions; and
  • define meaningful clinician participation in their activity, describe the mechanism for identifying clinicians who meet the requirements, and provide participant completion information.

Statement of Commercial Support

This activity is supported by educational grants from Biogen; Celgene Corporation; EMD Serono, Inc.; Genentech, Inc.; and Sanofi Genzyme.

There is no non-commercial support for this activity.

Education activities are distinguished as separate from endorsement of commercial products. When commercial products are displayed, participants will be advised that accredited status as a provider refers only to its continuing education activities and does not imply ANCC Commission on Accreditation endorsement of any commercial products.

Disclaimer Statement/Disclosure of Unlabeled Use

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2020 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME/CNE Questions?

Contact us at CME@VindicoCME.com

Activity Details

Free CME/CNE
1.75 AMA PRA Category 1 Credit(s)
1.75 Contact Hour(s)
Released: January 24, 2020
Expires: January 23, 2021
1.75 hours to complete

Accredited By

This continuing education activity is provided by

Endorsed by:

Target Audience

The intended audience for this activity is neurologists, neurology nurses, and other health care professionals involved in the management of patients with multiple sclerosis (MS).

Learning Objectives

Upon successful completion of this activity, participants should be better able to:
Physicians and Nurses:

  • Evaluate the latest clinical and/or real-world evidence regarding available and emerging disease-modifying therapies (DMTs) for MS management.
  • Assess the burden of comorbidities for patients with MS and implications for treatment, medication management, and quality of life.
  • Examine emerging clinical trends and controversies in MS that may impact future clinical decision making.
  • Incorporate appropriate shared decision-making strategies to engage patients with MS in their own care.

Physicians Only:

  • Identify patients with relapsing-remitting MS (RRMS) or progressive MS in a timely manner to ensure appropriate intervention.
  • Select treatment for patients with RRMS or progressive MS based on the latest clinical advances, patient risk, and evidence-based recommendations.

Activity Description

Multiple sclerosis (MS) is a chronic, often disabling disease that attacks the central nervous system. The management of patients with MS is highly complex, and the development of disease-modifying therapies (DMTs) has dramatically altered the treatment paradigm. Clinicians need to be updated on new evidence-based recommendations on the use of DMTs from the American Academy of Neurology Guidelines released in 2018. Another important aspect of caring for patients with MS is communication. Patients must be not only educated about their disease and treatment options, but also engaged in conversations about their risk tolerance, quality of life—including symptoms that they are experiencing—and any concerns they may have regarding their care. Shared decision-making is a model of 2-way communication between a patient and a provider with established ability to improve a patient’s satisfaction of care. In this CME/CNE activity, MS Forum® VI, current treatment guidelines, gender-based issues, environmental factors, and comorbidities in MS are discussed alongside the safety, efficacy, and use of current DMTs.

Faculty

Activity Chair

Patricia K. Coyle, MD, FAAN, FANA
Professor and Vice Chair (Clinical Affairs)
Department of Neurology
Director
Multiple Sclerosis Comprehensive Care Center
Stony Brook University Medical Center
Stony Brook, NY
Disclosures
Consulting Fee: Accordant, Actelion, Alexion, Bayer, Biogen, Celgene, EMD Serono, Genentech/Roche, Novartis, Sanofi Genzyme, TG Therapeutics
Contracted Research:
Actelion, Alkermes, Genentech/Roche, MedDay, NINDS, Novartis



Faculty

Bruce A. Cohen, MD, FAAN, FANA, FACP
Professor of Neurology
Northwestern University
Feinberg School of Medicine
Director
Northwestern Comprehensive Multiple Sclerosis Program
Chicago, IL
Disclosures
Consulting Fee:
Biogen, EMD Serono, Genentech, Mylan
Contracted Research: MedDay, Roche/Genentech



Clyde E. Markowitz, MD
Associate Professor of Neurology
Director, Multiple Sclerosis Center
Hospital of the University of Pennsylvania
Perelman School of Medicine
Philadelphia, PA
Disclosures
Consulting Fee: Actelion, Alexion, Bayer, Biogen Idec, Celgene, Genentech/Roche, Genzyme/Sanofi, Merck/EMD Serono, Novartis, Teva
Contracted Research: Actelion, Genentech/Roche, Novartis



Claire S. Riley, MD
Assistant Professor of Neurology
Medical Director, Columbia Multiple Sclerosis Center
Department of Neurology, Columbia University
New York, NY
Disclosures
Consulting Fee: Biogen Idec, EMD Serono, Genentech, Genzyme, TG Therapeutics
Contracted Research: Biogen Idec


Reviewer

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.


Nurse Planners

Barbara A. Niedz, PhD, RN, CPHQ
No relevant financial relationships to disclose.


Amy Perrin-Ross, APN, MSN, CNRN, MSCN
Consulting Fee: Celgene, Genentech, Genzyme, Mallinckrodt, Novartis, Roche
Speakers Bureau: Biogen, EMD Serono, Genentech, Genzyme, Mallinckrodt, Novartis, Teva


Staff

Vindico Medical Education
No relevant financial relationships to disclose.


Conflict of Interest Policy/Disclosure Statement

In accordance with the Accreditation Council for Continuing Medical Education and the American Nurses Credentialing Center’s (ANCC’s) Commission on Accreditation’s Standards for Commercial Support, all CME/CNE providers are required to disclose to the activity audience the relevant financial relationships of the planners, faculty, reviewers and staff involved in the development of CME/CNE content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the past 12 months with a commercial interest whose products or services are discussed in the CME/CNE activity content over which the individual has control.

Signed Disclosure(s) are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Vindico Medical Education, LLC, is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

Designation of Credit

Vindico Medical Education designates this enduring material for a maximum of 1.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Vindico Medical Education will provide 1.75 contact hours for nurses.

This enduring material is approved for 1 year from the date of original release, January 24, 2020 to January 23, 2021.

Instructions for Receiving Credit

To participate in this CME/CNE activity, you must read the objectives, answer the pretest questions, watch the presentations, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 4 out of 6 of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate or Learner-Paced Continuing Nursing Education Contact Hour Certificate.



MIPS Qualifying Activity
Vindico has identified this CME activity as an improvement activity in the Merit-Based Incentive Payment System (MIPS) of the Quality Payment Program (QPP). Participants who successfully complete the activity and its performance assessment will receive printable documentation of successful completion for MIPS self-reporting.

To meet the criteria for improvement activities in the MIPS of QPP, accredited CME providers need to implement activities that:

  • address a quality or safety gap that is supported by a needs assessment or problem analysis, or support the completion of such a needs assessment as part of the activity;
  • have specific, measurable aim(s) for improvement;
  • include interventions intended to result in improvement;
  • include data collection and analysis of performance data to assess the impact of the interventions; and
  • define meaningful clinician participation in their activity, describe the mechanism for identifying clinicians who meet the requirements, and provide participant completion information.

Statement of Commercial Support

This activity is supported by educational grants from Biogen; Celgene Corporation; EMD Serono, Inc.; Genentech, Inc.; and Sanofi Genzyme.

There is no non-commercial support for this activity.

Education activities are distinguished as separate from endorsement of commercial products. When commercial products are displayed, participants will be advised that accredited status as a provider refers only to its continuing education activities and does not imply ANCC Commission on Accreditation endorsement of any commercial products.

Disclaimer Statement/Disclosure of Unlabeled Use

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2020 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME/CNE Questions?

Contact us at CME@VindicoCME.com

1.00 CME
The France Foundation
Updates in SMA and Gene Therapy from Copenhagen

Updates in SMA and Gene Therapy from Copenhagen

Start

Activity Details

Free CME
1.0 AMA PRA Category 1 Credit(s)
Released: December 6, 2019
Expires: December 5, 2020
50 minutes to complete

Accredited By

Target Audience 

Neurologists, pediatricians, and general practitioners

Learning Objectives

After completing this activity, the participant should be better able to:

  • Explain status of newborn testing addition to screening panel in applicable states
  • Explain the implications of new gene therapy for SMA
  • Summarize key clinical trial data on novel treatments for SMA, with a focus on gene therapy
  • Explain key aspects of new guidance documents that inform up-to-date clinical practice

Activity Description

New information on spinal muscular atrophy was presented at an international meeting. Neuromuscular specialists share their perspective on the impact of this information on patient management in short videos about gene therapy, newborn screening, and therapeutic recommendations. These videos are available for viewing in English, Spanish, French, German, or English with Japanese or Arabic subtitles. Get up-to-date in 30 minutes in your own language.

Statement of Educational Need

The rapid influx of new information surrounding treatment for SMA has created a gap in clinician knowledge and the ability to apply it to practice. 

Agenda

Video topics

  • Exciting New Results in Patients Treated with Gene Therapy
  • Gene Therapy Biodistribution Study Results
  • Future Implications for SMA Therapy
  • SMN Copy Number and SMA Treatment
  • Encouraging Data from the Risdiplam Studies
  • Disease Progression in Untreated Patients
  • Early Detection and Early Treatment is Key
  • Evolving Assessments and Emerging Phenotypes in SMA
  • Status of Newborn Screening Varies by Country
  • Managing Patients with SMA

Faculty

Diana Castro, MD
Diana Castro, MD
Pediatric Neuromuscular Specialist
University of Texas, Southwestern
Dallas, TX

Dr. Castro has done contract research for AveXis, Biogen, PTC, Sarepta, and ReveraGen BioPharma.


Andreea Seferian, MD
Andreea Seferian, MD
Pediatric Neurologist
Myology Institute
I-Motion Institute
Armand Trousseau Hospital
Paris, France

Dr. Seferian has no relevant financial relationships to disclose.


Daniel Natera de Benito, MD, PhD
Daniel Natera de Benito, MD, PhD
Neuromuscular Disorders Unit 
Pediatric Neurology Department
Hospital Sant Joan de Déu
Barcelona, Spain

Dr. Natera de Benito has no relevant financial relationships to disclose.


Laurent Servais, MD
Laurent Servais, MD
Professor of Pediatric Neuromuscular Diseases
MDUK Oxford Neuromuscular Center
University of Oxford
Oxford, United Kingdom

Dr. Servais serves on advisory boards for AveXis, Biogen, Cytokinetics, and Roche. He also does contract research for AveXis, Biogen, and Roche. 


Prof. Dr. Maggie C. Walter, MA
Prof. Dr. Maggie C. Walter, MA
Friedrich Baur Institute
Department of Neurology
Ludwig-Maximilians-University
Munich, Germany

Dr. Walter is a consultant for Ask Bio, AveXis, Pharnext, and PTC Therapeutics. She serves on the advisory boards for AveXis, Biogen, PTC Therapeutics, and Sarepta. Dr. Walter also does contract research for Pharnext and receives grant funding from Biogen, Pharnext, PTC Therapeutics, Santhera, and Sarepta.


Activity Staff Disclosures
The planners, reviewers, editors, staff, CME committee, or other members at The France Foundation who control content have no relevant financial relationships to disclose.

Conflict of Interest Policy/Disclosure Statement

In accordance with the ACCME Standards for Commercial Support, The France Foundation (TFF) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. TFF resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs. Furthermore, TFF seeks to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. TFF is committed to providing learners with high-quality CME/CE activities that promote improvements in healthcare and not those of a commercial interest.

Accreditation Statement

The France Foundation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation of Credit

Physicians
The France Foundation designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses
Nurses who are certified by the American Nurses Credentialing Center (ANCC) may utilize activities that are certified by ACCME-accredited providers toward their requirement for certification renewal by the ANCC. A certificate of attendance will be provided by The France Foundation, an ACCME accredited provider.

Method of Participation/How to Receive Credit

  1. There are no fees for participating in and receiving credit for this activity.
  2. Review the activity objectives and CME/CE information.
  3. Complete the CME/CE activity.
  4. Complete the online posttest. A score of at 100% is required to successfully complete this activity. The participant may take the test until successfully passed.
  5. Complete the CME/CE evaluation/attestation form, which provides each participant with the opportunity to comment on how participating in the activity will affect their professional practice; the quality of the instructional process; the perception of enhanced professional effectiveness; the perception of commercial bias; and his/her views on future educational needs.
    • If you are requesting AMA PRA Category 1 Credits™ or a certificate of participation—your CME/CE certificate will be available for download.
  6. Credit documentation/reporting:

Statement of Commercial Support

This activity is supported by an educational grant from AveXis, Inc.

Disclosure of Unlabeled Use

TFF requires CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental, and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of U.S. Food and Drug Administration approved labeling. This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. TFF does not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.

Disclaimer

The France Foundation presents this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The France Foundation and the commercial supporter(s) assume no liability for the information herein.

Contact Information

If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or info@francefoundation.com.

Activity Details

Free CME
1.0 AMA PRA Category 1 Credit(s)
Released: December 6, 2019
Expires: December 5, 2020
50 minutes to complete

Accredited By

Target Audience 

Neurologists, pediatricians, and general practitioners

Learning Objectives

After completing this activity, the participant should be better able to:

  • Explain status of newborn testing addition to screening panel in applicable states
  • Explain the implications of new gene therapy for SMA
  • Summarize key clinical trial data on novel treatments for SMA, with a focus on gene therapy
  • Explain key aspects of new guidance documents that inform up-to-date clinical practice

Activity Description

New information on spinal muscular atrophy was presented at an international meeting. Neuromuscular specialists share their perspective on the impact of this information on patient management in short videos about gene therapy, newborn screening, and therapeutic recommendations. These videos are available for viewing in English, Spanish, French, German, or English with Japanese or Arabic subtitles. Get up-to-date in 30 minutes in your own language.

Statement of Educational Need

The rapid influx of new information surrounding treatment for SMA has created a gap in clinician knowledge and the ability to apply it to practice. 

Agenda

Video topics

  • Exciting New Results in Patients Treated with Gene Therapy
  • Gene Therapy Biodistribution Study Results
  • Future Implications for SMA Therapy
  • SMN Copy Number and SMA Treatment
  • Encouraging Data from the Risdiplam Studies
  • Disease Progression in Untreated Patients
  • Early Detection and Early Treatment is Key
  • Evolving Assessments and Emerging Phenotypes in SMA
  • Status of Newborn Screening Varies by Country
  • Managing Patients with SMA

Faculty

Diana Castro, MD
Diana Castro, MD
Pediatric Neuromuscular Specialist
University of Texas, Southwestern
Dallas, TX

Dr. Castro has done contract research for AveXis, Biogen, PTC, Sarepta, and ReveraGen BioPharma.


Andreea Seferian, MD
Andreea Seferian, MD
Pediatric Neurologist
Myology Institute
I-Motion Institute
Armand Trousseau Hospital
Paris, France

Dr. Seferian has no relevant financial relationships to disclose.


Daniel Natera de Benito, MD, PhD
Daniel Natera de Benito, MD, PhD
Neuromuscular Disorders Unit 
Pediatric Neurology Department
Hospital Sant Joan de Déu
Barcelona, Spain

Dr. Natera de Benito has no relevant financial relationships to disclose.


Laurent Servais, MD
Laurent Servais, MD
Professor of Pediatric Neuromuscular Diseases
MDUK Oxford Neuromuscular Center
University of Oxford
Oxford, United Kingdom

Dr. Servais serves on advisory boards for AveXis, Biogen, Cytokinetics, and Roche. He also does contract research for AveXis, Biogen, and Roche. 


Prof. Dr. Maggie C. Walter, MA
Prof. Dr. Maggie C. Walter, MA
Friedrich Baur Institute
Department of Neurology
Ludwig-Maximilians-University
Munich, Germany

Dr. Walter is a consultant for Ask Bio, AveXis, Pharnext, and PTC Therapeutics. She serves on the advisory boards for AveXis, Biogen, PTC Therapeutics, and Sarepta. Dr. Walter also does contract research for Pharnext and receives grant funding from Biogen, Pharnext, PTC Therapeutics, Santhera, and Sarepta.


Activity Staff Disclosures
The planners, reviewers, editors, staff, CME committee, or other members at The France Foundation who control content have no relevant financial relationships to disclose.

Conflict of Interest Policy/Disclosure Statement

In accordance with the ACCME Standards for Commercial Support, The France Foundation (TFF) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. TFF resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs. Furthermore, TFF seeks to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. TFF is committed to providing learners with high-quality CME/CE activities that promote improvements in healthcare and not those of a commercial interest.

Accreditation Statement

The France Foundation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation of Credit

Physicians
The France Foundation designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses
Nurses who are certified by the American Nurses Credentialing Center (ANCC) may utilize activities that are certified by ACCME-accredited providers toward their requirement for certification renewal by the ANCC. A certificate of attendance will be provided by The France Foundation, an ACCME accredited provider.

Method of Participation/How to Receive Credit

  1. There are no fees for participating in and receiving credit for this activity.
  2. Review the activity objectives and CME/CE information.
  3. Complete the CME/CE activity.
  4. Complete the online posttest. A score of at 100% is required to successfully complete this activity. The participant may take the test until successfully passed.
  5. Complete the CME/CE evaluation/attestation form, which provides each participant with the opportunity to comment on how participating in the activity will affect their professional practice; the quality of the instructional process; the perception of enhanced professional effectiveness; the perception of commercial bias; and his/her views on future educational needs.
    • If you are requesting AMA PRA Category 1 Credits™ or a certificate of participation—your CME/CE certificate will be available for download.
  6. Credit documentation/reporting:

Statement of Commercial Support

This activity is supported by an educational grant from AveXis, Inc.

Disclosure of Unlabeled Use

TFF requires CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental, and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of U.S. Food and Drug Administration approved labeling. This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. TFF does not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.

Disclaimer

The France Foundation presents this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The France Foundation and the commercial supporter(s) assume no liability for the information herein.

Contact Information

If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or info@francefoundation.com.

0.50-1.50 CME
The France Foundation
SMA Updates From Around the World

SMA Updates From Around the World

Start

Activity Details

Free CME
0.50-1.50 AMA PRA Category 1 Credit(s)
Released: November 26, 2019
Expires: November 25, 2020
Varies from 30 minutes to 90 minutes to complete

Accredited By


Target Audience

Neurologists, genetic counselors, neuromuscular specialists, nurses, and nurse practitioners

Learning Objectives

After completing this activity, the participant should be better able to:
  • Review information on the management of patients with SMA released at major conferences in 2019
  • Apply emerging information to current SMA management practices, as relevant

Activity Description

Researchers and clinicians interested in spinal muscular atrophy discuss new developments from national and international neuromuscular conferences. In this activity, choose which video to watch on a range of topics from diagnosis to clinical trial updates and implications of new available therapies.

Statement of Educational Need

The rapid influx of new information surrounding treatment for SMA has created a gap in clinician knowledge and the ability to apply it to practice.

Agenda

Video topics
  • Diagnosis of Spinal Muscular Atrophy
  • NURTURE and SHINE Study Data
  • Risdiplam Clinical Trial Data
  • Nusinersen in Adult Patients
  • Gene Therapy Data
  • Implications of New Therapies
  • New Outcomes Measures
  • Patient Management

Faculty

Gyula Acsadi, MD, PhD
Division Head of Neurology and Rehabilitation
Professor of Pediatric Neurology
Connecticut Children’s Medical Center
Hartford, CT
  • Dr. Acsadi does consulting for AveXis, Biogen, and Sarepta; serves on the speaker’s bureau for Biogen; and does contract research for Biogen, Italfarmaco, and Sarepta.


Lisa Belter, MPH
Senior Research Analyst
Cure SMA
Elk Grove Village, IL
  • Ms. Belter has no relevant financial relationships to disclose.


Diana Castro, MD
Pediatric Neuromuscular Specialist
University of Texas, Southwestern
Dallas, TX
  • Dr. Castro has done contract research for AveXis, Biogen, PTC, Sarepta, and ReveraGen BioPharma.


Mary Curry, ND
Senior Manager, Clinical Affairs
Cure SMA
Elk Grove Village, IL
  • Dr. Curry has no relevant financial relationships to disclose.


Richard S. Finkel, MD
Division Chief of Neurology
Pediatric Neurology
Nemours Children’s Hospital
Orlando, FL
  • Dr. Finkel serves on the advisory board for AveXis, Biogen, Catabasis, Neurogene, Roche, and Sarepta. He does contract research for AveXis, Biogen, Catabasis, Cytokinetics, Capricor, Italfarmaco, Pfizer, ReveraGen, Roche, Sarepta, and Summit. He receives royalties from Children’s Hospital of Philadelphia and Elsevier.


Vamshi Rao, MD
Attending Physician, Neurology
Ann & Robert Lurie Children’s Hospital of Chicago
Chicago, IL
  • Dr. Rao does consulting for AveXis, Biogen, PTC, and Sarepta. He does contract research for Alexion, NSPharma, and Solid Biosciences.


Perry Shieh, MD, PhD
Associate Professor of Neurology
UCLA Medical Center
Los Angeles, CA
  • Dr. Shieh has done consulting for AveXis, Biogen, Genentech, PTC, and Sarepta. He serves on speakers’ bureaus for Alexion, AMO Pharma, Behring, Biogen, CSL, and Grifols. He does contract research for Acceleron, Audentes, Avexis, Biogen, Catabasis, Catalyst, Cytokinetics, Italfarmico, Pfizer, PTC, Ra Pharma, Reata, ReveraGen BioPharma, Roche, Sanofi, Santhera, Sarepta, and Summit.


Aravindhan Veerapandiyan, MD
Pediatric Neurologist
Arkansas Children’s Hospital
Little Rock, AR
  • Dr. Veerapandiyan has no relevant financial relationships to disclose.


Activity Staff Disclosures
The planners, reviewers, editors, staff, CME committee, or other members at The France Foundation who control content have no relevant financial relationships to disclose.

Conflict of Interest Policy/Disclosure Statement

In accordance with the ACCME Standards for Commercial Support, The France Foundation (TFF) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. TFF resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs. Furthermore, TFF seeks to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. TFF is committed to providing learners with high-quality CME/CE activities that promote improvements in healthcare and not those of a commercial interest.

Accreditation Statement

The France Foundation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation of Credit

Physicians
The France Foundation designates this enduring activity for a maximum of 1.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses
Nurses who are certified by the American Nurses Credentialing Center (ANCC) may utilize activities that are certified by ACCME-accredited providers toward their requirement for certification renewal by the ANCC. A certificate of attendance will be provided by The France Foundation, an ACCME accredited provider.

Method of Participation/How to Receive Credit

  • There are no fees for participating in and receiving credit for this activity.
  • Review the activity objectives and CME/CE information.
  • Complete the CME/CE activity.
  • Complete the online posttest. A score of at least 60% is required to successfully complete this activity. The participant may take the test until successfully passed.
  • Complete the CME/CE evaluation/attestation form, which provides each participant with the opportunity to comment on how participating in the activity will affect their professional practice; the quality of the instructional process; the perception of enhanced professional effectiveness; the perception of commercial bias; and his/her views on future educational needs.
  • Credit documentation/reporting:
    • If you are requesting AMA PRA Category 1 Credits™ or a certificate of participation—your CME/CE certificate will be available for download.

Statement of Commercial Support

This activity is supported by educational grants from Biogen and Genentech, Inc.

Disclosure of Unlabeled Use

TFF requires CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of U.S. Food and Drug Administration approved labeling. This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. TFF does not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.

Disclaimer

The France Foundation presents this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The France Foundation and the commercial supporter(s) assume no liability for the information herein.

Contact Information

If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or info@francefoundation.com.

Activity Details

Free CME
0.50-1.50 AMA PRA Category 1 Credit(s)
Released: November 26, 2019
Expires: November 25, 2020
Varies from 30 minutes to 90 minutes to complete

Accredited By


Target Audience

Neurologists, genetic counselors, neuromuscular specialists, nurses, and nurse practitioners

Learning Objectives

After completing this activity, the participant should be better able to:
  • Review information on the management of patients with SMA released at major conferences in 2019
  • Apply emerging information to current SMA management practices, as relevant

Activity Description

Researchers and clinicians interested in spinal muscular atrophy discuss new developments from national and international neuromuscular conferences. In this activity, choose which video to watch on a range of topics from diagnosis to clinical trial updates and implications of new available therapies.

Statement of Educational Need

The rapid influx of new information surrounding treatment for SMA has created a gap in clinician knowledge and the ability to apply it to practice.

Agenda

Video topics
  • Diagnosis of Spinal Muscular Atrophy
  • NURTURE and SHINE Study Data
  • Risdiplam Clinical Trial Data
  • Nusinersen in Adult Patients
  • Gene Therapy Data
  • Implications of New Therapies
  • New Outcomes Measures
  • Patient Management

Faculty

Gyula Acsadi, MD, PhD
Division Head of Neurology and Rehabilitation
Professor of Pediatric Neurology
Connecticut Children’s Medical Center
Hartford, CT
  • Dr. Acsadi does consulting for AveXis, Biogen, and Sarepta; serves on the speaker’s bureau for Biogen; and does contract research for Biogen, Italfarmaco, and Sarepta.


Lisa Belter, MPH
Senior Research Analyst
Cure SMA
Elk Grove Village, IL
  • Ms. Belter has no relevant financial relationships to disclose.


Diana Castro, MD
Pediatric Neuromuscular Specialist
University of Texas, Southwestern
Dallas, TX
  • Dr. Castro has done contract research for AveXis, Biogen, PTC, Sarepta, and ReveraGen BioPharma.


Mary Curry, ND
Senior Manager, Clinical Affairs
Cure SMA
Elk Grove Village, IL
  • Dr. Curry has no relevant financial relationships to disclose.


Richard S. Finkel, MD
Division Chief of Neurology
Pediatric Neurology
Nemours Children’s Hospital
Orlando, FL
  • Dr. Finkel serves on the advisory board for AveXis, Biogen, Catabasis, Neurogene, Roche, and Sarepta. He does contract research for AveXis, Biogen, Catabasis, Cytokinetics, Capricor, Italfarmaco, Pfizer, ReveraGen, Roche, Sarepta, and Summit. He receives royalties from Children’s Hospital of Philadelphia and Elsevier.


Vamshi Rao, MD
Attending Physician, Neurology
Ann & Robert Lurie Children’s Hospital of Chicago
Chicago, IL
  • Dr. Rao does consulting for AveXis, Biogen, PTC, and Sarepta. He does contract research for Alexion, NSPharma, and Solid Biosciences.


Perry Shieh, MD, PhD
Associate Professor of Neurology
UCLA Medical Center
Los Angeles, CA
  • Dr. Shieh has done consulting for AveXis, Biogen, Genentech, PTC, and Sarepta. He serves on speakers’ bureaus for Alexion, AMO Pharma, Behring, Biogen, CSL, and Grifols. He does contract research for Acceleron, Audentes, Avexis, Biogen, Catabasis, Catalyst, Cytokinetics, Italfarmico, Pfizer, PTC, Ra Pharma, Reata, ReveraGen BioPharma, Roche, Sanofi, Santhera, Sarepta, and Summit.


Aravindhan Veerapandiyan, MD
Pediatric Neurologist
Arkansas Children’s Hospital
Little Rock, AR
  • Dr. Veerapandiyan has no relevant financial relationships to disclose.


Activity Staff Disclosures
The planners, reviewers, editors, staff, CME committee, or other members at The France Foundation who control content have no relevant financial relationships to disclose.

Conflict of Interest Policy/Disclosure Statement

In accordance with the ACCME Standards for Commercial Support, The France Foundation (TFF) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. TFF resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs. Furthermore, TFF seeks to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. TFF is committed to providing learners with high-quality CME/CE activities that promote improvements in healthcare and not those of a commercial interest.

Accreditation Statement

The France Foundation is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation of Credit

Physicians
The France Foundation designates this enduring activity for a maximum of 1.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses
Nurses who are certified by the American Nurses Credentialing Center (ANCC) may utilize activities that are certified by ACCME-accredited providers toward their requirement for certification renewal by the ANCC. A certificate of attendance will be provided by The France Foundation, an ACCME accredited provider.

Method of Participation/How to Receive Credit

  • There are no fees for participating in and receiving credit for this activity.
  • Review the activity objectives and CME/CE information.
  • Complete the CME/CE activity.
  • Complete the online posttest. A score of at least 60% is required to successfully complete this activity. The participant may take the test until successfully passed.
  • Complete the CME/CE evaluation/attestation form, which provides each participant with the opportunity to comment on how participating in the activity will affect their professional practice; the quality of the instructional process; the perception of enhanced professional effectiveness; the perception of commercial bias; and his/her views on future educational needs.
  • Credit documentation/reporting:
    • If you are requesting AMA PRA Category 1 Credits™ or a certificate of participation—your CME/CE certificate will be available for download.

Statement of Commercial Support

This activity is supported by educational grants from Biogen and Genentech, Inc.

Disclosure of Unlabeled Use

TFF requires CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of U.S. Food and Drug Administration approved labeling. This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. TFF does not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.

Disclaimer

The France Foundation presents this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The France Foundation and the commercial supporter(s) assume no liability for the information herein.

Contact Information

If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or info@francefoundation.com.

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